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Genetic Copycatchers Detect Efficient and Precise CRISPR Editing in a Living Organism – SciTechDaily

Proof-of-principle research shows that genes can be accurately edited in cells throughout the body. Researchers at the University of California San Diego have laid…

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Red fluorescent detector proteins in fruit flies reveal detection from an actual copying experiment (left) and how perfect copying would appear (right). Fluorescent cells in the left panel also lack the function of a pigmentation gene called “pale” due to copying of the CopyCatcher element, which eliminates function of both copies of the pale gene. Control flies in the right panel, which have only one copy of the pale gene disrupted by insertion of the CopyCatcher (one functional copy of the gene),…

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